A comprehensive compilation of methods in constraint-based reconstruction and analysis
Welcome to the home of a comprehensive catalog of constraint-based methods and software packages. This contains detailed information for all methods that have been derived from Flux Balance Analysis, Elementary Flux Mode Analysis, and Extreme Pathway Analysis.
This site is accompanied by a comprehensive review on methods in constraint-based modeling:
Lewis NE, Nagarajan H, Palsson BO. Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods. Nature Reviews Microbiology. (2012)
We invite the constraint-based community to contribute to descriptions on new or existing constraint-based methods. For information on acquiring editing permissions for this site, click here.
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