Elementary Modes
General concept
Elementary modes represent the generating vectors of the flux polytope. These pathways can be combined to describe any feasible steady state flux distribution.
Items to consider when implementing
Software packages with this method
Applications of interest
Terzer and Stelling, provided an algorithmic improvement on this approach using bit pattern trees.
Relevant references
Schuster S, Hilgetag C.On elementary flux modes in biochemical reaction systems at steady state. Journal of Biological Systems.
2(2), 165-182 (1994) DOI: 10.1142/S0218339094000131
Terzer M, Stelling J. Large-scale computation of elementary flux modes with bit pattern trees. Bioinformatics. 2008 Oct 1;24(19):2229-35.
Related methods
page revision: 1, last edited: 17 Aug 2012 04:59