OptReg
General concept
Desired products can be obtained not only through the deletion of extant metabolic reactions, but also through the up- and down-regulation of other reactions. These modifications can be identified in silico. This method extends OptKnock by providing additional variables and non-linearities. These additions allow for the prediction of reactions that can be up- or down-regulated to aid in strain design.
Items to consider when implementing
Software packages with this method
Applications of interest
Description of study and link to study:
What was learned with this method:
Relevant references
Related methods
page revision: 0, last edited: 02 Apr 2013 19:57