COBRA without mass balance
General concept
The Von Neumann model is applied to metabolism, without requiring mass balance or stationarity of flux. However, these are essentially recovered at maximum growth. This shows, however that mass balance is met for almost all metabolites, suggesting a correction for FBA.
Items to consider when implementing
Software packages with this method
Applications of interest
Description of study and link to study:
What was learned with this method:
Relevant references
Related methods
page revision: 0, last edited: 02 Apr 2013 18:14