Constraining flux through integration of gene expression data

General concept

When transcriptomic data suggest a gene is not expressed or a member of a complex is not expressed, the associated flux is set to zero.

Items to consider when implementing

Software packages with this method

Applications of interest

Relevant references

Akesson M, Förster J, Nielsen J. Integration of gene expression data into genome-scale metabolic models. Metab Eng. 2004 Oct;6(4):285-93.

Related methods


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