Drug Off-Target Effects Predicted Using Structural Analysis in the Context of a Metabolic Network Model

General concept

A metabolite of interest is docked on all metabolic enzyme structures. The reactions associated with these enzymes are perturbed in the metabolic network, and modeled using FBA.

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Software packages with this method

Applications of interest

Description of study and link to study:

What was learned with this method:

Relevant references

Chang et al

Related methods

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