Dynamic FBA (DFBA)

General concept

In DFBA, constraints are placed the rate at which fluxes can change when there is a change in media conditions. This can be implemented using nonlinear programming or by using linear programming on a series of short time intervals. This was first done by Varma and Palsson, 1994 and the approach was also published by Mahadevan, et al., 2002

Items to consider when implementing

Software packages with this method

Applications of interest

Description of study and link to study:

What was learned with this method:

Relevant references

Varma and Palsson
Mahadevan, et al.

Related methods

Flux Balance Analysis


Dynamic multi-species metabolic modeling (DMMM)

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