Network-based enzyme localization
General concept
Localization of metabolic reactions in different compartments is predicted using a parsimony principle of minimizing the number of cross-membrane transporters. Using a set of known reaction localization calls, an MILP problem is solved to minimize the number of reactions and transporters needed to link a known reactions to make known reactions functional with the rest of the network.
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Applications of interest
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page revision: 0, last edited: 02 Apr 2013 18:57