Noninferior set estimation (NISE) for multiobjective balancing
General concept
FBA computes solutions to single objectives, while in reality, cells might be balancing several cellular objectives. Thus, a multiple objective approach is suggested. The NISE generates an approximation of the Pareto curve showing the balance between multiple competing objectives. This is done without having to iterate single objective optimizations. This method also allows the investigation of flux distributions for each Pareto optimal solution.
Items to consider when implementing
Software packages with this method
Applications of interest
Description of study and link to study:
What was learned with this method:
Relevant references
Related methods
page revision: 0, last edited: 02 Apr 2013 19:19