OptCom

General concept

OptCom presents an optimization framework to study the metabolic modeling of microbial communities. This approach optimizes for a multi-level objective to account for the trade-offs between individual fitness and community level fitness.

Items to consider when implementing

Software packages with this method

Applications of interest

Relevant references

Zomorrodi AR, Maranas CD. OptCom: A Multi-Level Optimization Framework for the Metabolic Modeling and Analysis of Microbial Communities. PLoS Comput Biol. 2012 Feb;8(2):e1002363.

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