OptForce

General concept

OptForce identifies the possible genetic manipulations by classifying whether the reaction flux must change to meet the overproduction of a particular compound of interest. The method further identifies a minimal set of fluxes that must be forced through manipulations so that the network is consistent with the overall objective of overproduction of the compound of interest.

Items to consider when implementing

Software packages with this method

Applications of interest

Description of study and link to study:

What was learned with this method:

Relevant references

Ranganathan, et al.

Related methods

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