Regulatory FBA (rFBA)

General concept

Transcription regulation can be incorporated into constraint-based models of metabolism. This is done by imposing Boolean constraints on reaction fluxes, based on concentrations of metabolites in the in silico media.

Items to consider when implementing

Software packages with this method

Applications of interest

Description of study and link to study:

What was learned with this method:

Relevant references

Covert, et al.

Related methods