Search for Exchanged Metabolites (SEM)

General concept

This MILP problem finds the minimal set of exchanged metabolites between two organisms that are growing together in a specified medium. Growth is fixed to a minimum rate on both models and then minimizing the number of metabolites that are exchanged between the organisms.

Items to consider when implementing

Software packages with this method

Applications of interest

Description of study and link to study:

What was learned with this method:

Relevant references

Klitgord and Segre

Related methods

Unless otherwise stated, the content of this page is licensed under Creative Commons Attribution-ShareAlike 3.0 License