Shlomi NBT 08

General concept

Method to integrate omic data with metabolic models. MILP framework that generates a context-specific model by maximizing the number of reactions whose flux levels are consistent with the expression data of the corresponding genes. A web-based implementation has be made, called iMAT.

Items to consider when implementing

Software packages with this method

COBRA toolbox

Applications of interest

Description of study and link to study:

What was learned with this method:

Relevant references

Shlomi, et al.

Related methods

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