Transcriptional-controlled FBA (tFBA)
General concept
This approach uses regulatory up/down constraints based on differential gene expression data in FBA optimization. An MILP is formulated that minimizes the number of violated up/down constraints between models under the two given substrates.
Items to consider when implementing
Software packages with this method
Applications of interest
Description of study and link to study:
What was learned with this method:
Relevant references
Related methods
page revision: 0, last edited: 02 Apr 2013 19:30